Infectious Diseases

//Infectious Diseases

CNPRC Core Scientist Tapped for Chancellor’s Achievement Award

Media Contact: Carlos Villatoro (530) 754 4413 (UC Davis) - California National Primate Research Center Core Scientist Dr. Koen Van Rompay was recently honored for his work, both in and out of the lab, with a Chancellor's Achievement Award  in Diversity and Community. Dr. Van Rompay was among [...]

2017-08-30T23:07:05+00:00 February 24th, 2017|

NIH Releases NHP Workshop Report

(UC DAVIS, Calif.) – The National Institutes of Health (NIH) released a report today centering on a recent workshop that explored the use of non-human primates (NHPs) in medical research. The workshop, held Sept. 7, 2016, and entitled “Ensuring the Continued Responsible Oversight of Research with Non-Human Primates” brought together [...]

2017-08-30T23:07:05+00:00 January 19th, 2017|

CNPRC Puts Call Out for 2017 Pilot Project Letters of Intent

Contact: Carlos Villatoro (530) 754-4413 (UC DAVIS, Calif.) – The California National Primate Research Center (CNPRC) Pilot Program invites Letters of Intent for pilot project proposals to support basic and translational research using nonhuman primates (rhesus macaque and titi monkeys) for the 2017-2018 funding period.  Pilot projects that address biomedical/translational research topics across [...]

2017-08-30T23:07:05+00:00 January 13th, 2017|Tags: |

Fox 40 Talks Zika With Dr. Koen Van Rompay

Media Contact: Carlos Villatoro (530) 754-4413 Fox 40 cameras visited the California National Primate Research Center on Monday, Sept. 26, 2016, to interview Dr. Koen Van Rompay about the center's Zika Virus Project. Dr. Van Rompay spoke with Fox 40's Joe Khalil about the Zika project and showed him [...]

2016-10-11T18:16:36+00:00 September 27th, 2016|Tags: , , |

HIV Vaccine Developed Through Primate Centers Collaboration

Moving towards human clinical trials Over the past 6 years, Drs. Peter Barry and Alice Tarantal, California National Primate Research Center (CNPRC) at UC Davis, have been collaborating with Dr. Louis Picker at Oregon Health Science University (OHSU)–Oregon NPRC to develop and test a vaccine and potential cure for HIV. [...]

Understanding Zika Virus with Nonhuman Primates

Developing a strategy to prevent and treat Zika virus Research is beginning next week at the California National Primate Research Center (CNPRC) at UC Davis to understand Zika virus. Leading the efforts are Drs. Koen Van Rompay, Eliza Bliss-Moreau, Paul Luciw and John H. Morrison at the CNPRC, and Dr. [...]

Mother-to-infant transmission of high-risk infection: new monkey model

Dr. Peter Barry’s innovative research program using the rhesus monkey as a model of CMV infection leads to a successful study in placental transmission Cytomegalovirus (CMV) infection is highly prevalent in humans, infecting from 50-100% of adults around the world. The virus is often contracted through contact with saliva or [...]

Director Morrison: A Leader in Outreach

“There is no question that this is an exciting time for neuroscience. These major projects around the globe give us great opportunities to let the public know about why our work is important.” John Morrison, PhD, is the director of the California National Primate Research Center at the University of [...]

The Challenge of Controlling HIV

A new understanding of how some infants may resist HIV disease When a person is infected with a virus their immune system is normally activated to respond to and control the infection. However, when a person is persistently infected with HIV, the chronic activation and overstimulation of the immune system [...]

MERIT Program Announced at CNPRC

Igniting Novel Research with Current and New Animal Models Drug discovery and innovative therapeutic approaches in the era of personalized medicine requires the use of animal models that closely recapitulate human disease. To address these challenges, the California National Primate Research Center (CNPRC) at UC Davis is initiating the MERIT [...]

CNPRC Study Leads to Meningococcal Vaccine Improvements

On February 12, 2015, CNPRC Affiliate Scientists Drs. Koen Van Rompay, Peter Beernink, and Dan Granoff announced important findings from a pilot project study conducted at the CNPRC on improving the effectiveness of the meningococcal vaccine for prevention of sepsis and meningitis caused by meningococci group B, a rare, and sometimes [...]

Evaluating Measles Vaccine Safety

High rates of non-vaccinated children throughout the US have reached critical numbers of vulnerable individuals, resulting in perfect conditions for a wildfire storm of measles infections, an easily preventable yet highly contagious disease. More than 120 confirmed cases of measles have been reported in 17 states and the District of [...]

2017-08-30T23:07:09+00:00 February 18th, 2015|Tags: , , , , , |

Vaccine against HCMV, the “birth defect virus”, produces a strong immune response

An exciting new vaccine strategy was recently announced by Director Peter Barry and colleagues at City of Hope that has the potential to prevent a viral infection that causes 5,000 babies yearly to be born with congenital neurological deficits. Human cytomegalovirus, or HCMV, is a common virus, infecting from 50-100% [...]

Mother’s immunity linked to brain inflammation

Monkeys exposed in utero to their mother’s immune response to a mock infection show inflammation in their brains four years later, similar to which can be associated with schizophrenia and autism. Melissa Bauman presented new findings in her research in brain inflammation in monkeys at the 2014 Society for Neuroscience annual meeting [...]

2017-10-03T18:20:33+00:00 November 25th, 2014|Tags: , , , , , |

Early HIV infection and potential therapeutic targets

What is potentially exciting about this research is the demonstration that the early stages of gut inflammation and damage can be intervened by the targeted probiotic bacteria. The mucosal lining of the human gastrointestinal tract is on the frontline of immune defenses, crucial in preventing infection and controlling the spread of [...]

2017-08-30T23:07:09+00:00 October 30th, 2014|Tags: , , , |

Linking CNPRC research with patients

“For myself and the thousands of people your research efforts may someday impact I want to thank you and wish you the best.” J., CMV patient As a busy Director of both the CNPRC and the Center for Comparative Medicine, Dr. Peter Barry makes time in his hectic schedule to [...]

2017-08-30T23:07:09+00:00 October 16th, 2014|

Breast- and Bottle-fed Infant Monkeys Develop Different Immune System

In a study published in Science Translational Medicine on September 3, 2014, researchers from the California National Primate Research Center (CNPRC) at UC Davis and from UC San Francisco have shown that breast-and bottle-fed infant rhesus macaques develop different immune systems. Although the researchers expected that different diets would promote [...]

2017-08-30T23:07:09+00:00 September 3rd, 2014|Tags: , , , , , |

Nonhuman Primates and Ebola Virus Treatments and Vaccines

The recent deadly outbreak of Ebola virus in West Africa has highlighted the key role of nonhuman primate biomedical research in developing critically needed treatments and vaccines for emerging infectious diseases. Scientists around the world have pursued different strategies for development of a preventative vaccine and an effective treatment for [...]

2017-08-30T23:07:10+00:00 August 6th, 2014|

Why Primate Models Matter

Scientists discuss the importance of primate models for advancing knowledge in biomedical and biological research. Presenting an honest, forthright discussion of the ethical considerations of using nonhuman primates (NHP) in research, and demonstrating the vital role NHP have played in many of the medical and scientific advances of the past [...]

2017-08-30T23:07:10+00:00 April 15th, 2014|Tags: , |

Vaccine Fends off Virus that Strikes Weak Immune Systems

An experimental vaccine modeling human cytomegalovirus (HCMV) infection — which can endanger developing fetuses, transplant recipients, patients co-infected with HIV and others who have a weakened immune system — proved safe and effective in research conducted at the CNPRC using the rhesus macaque model. A team of scientists from the [...]

2017-08-30T23:07:10+00:00 November 8th, 2013|Tags: , |