Reproductive Sciences And Regenerative Medicine

//Reproductive Sciences And Regenerative Medicine

California National Primate Research Center Successfully Demonstrates Gene Editing in Nonhuman Primates

Media Contact: Carlos Villatoro (530) 754 4413 (U.C. DAVIS) – Imagine a world where maladies such as cystic fibrosis, Huntington’s Disease, or sickle cell anemia no longer exist. While the U.S. is far from achieving this lofty goal, it recently came a step closer at the California National Primate [...]

Podcast – Vasalgel Study at CNPRC

Contact: Carlos Villatoro (530) 754-4413 In this edition of "Monkey Talk" we talk with Dr. Catherine VandeVoort about her recent Vasalgel study at the California National Primate Research Center. Vasalgel is a polymer-based hydrogel that acts much like a vasectomy, however, it is reversible. To read more about Dr. VandeVoort's study [...]

Vasectomy Alternative Gets Boost at CNPRC

Media Contact: Carlos Villatoro (530) 754 4413 Successful application of an alternative male contraceptive in rhesus macaque monkeys at the California National Primate Research Center paves the way for human clinical trials (U.C. DAVIS) – For over a century men who did not want to father a child had but [...]

2017-02-07T18:42:37+00:00 February 7th, 2017|Tags: , , , |

NIH Releases NHP Workshop Report

(UC DAVIS, Calif.) – The National Institutes of Health (NIH) released a report today centering on a recent workshop that explored the use of non-human primates (NHPs) in medical research. The workshop, held Sept. 7, 2016, and entitled “Ensuring the Continued Responsible Oversight of Research with Non-Human Primates” brought together [...]

2017-08-30T23:07:05+00:00 January 19th, 2017|

CNPRC Puts Call Out for 2017 Pilot Project Letters of Intent

Contact: Carlos Villatoro (530) 754-4413 (UC DAVIS, Calif.) – The California National Primate Research Center (CNPRC) Pilot Program invites Letters of Intent for pilot project proposals to support basic and translational research using nonhuman primates (rhesus macaque and titi monkeys) for the 2017-2018 funding period.  Pilot projects that address biomedical/translational research topics across [...]

2017-08-30T23:07:05+00:00 January 13th, 2017|Tags: |

Mother-to-infant transmission of high-risk infection: new monkey model

Dr. Peter Barry’s innovative research program using the rhesus monkey as a model of CMV infection leads to a successful study in placental transmission Cytomegalovirus (CMV) infection is highly prevalent in humans, infecting from 50-100% of adults around the world. The virus is often contracted through contact with saliva or [...]

Director Morrison: A Leader in Outreach

“There is no question that this is an exciting time for neuroscience. These major projects around the globe give us great opportunities to let the public know about why our work is important.” John Morrison, PhD, is the director of the California National Primate Research Center at the University of [...]

Aging and Synaptic Health

CNPRC Incoming Director John Morrison is expanding our understanding of how estrogen affects cognitive functioning and synaptic health The good, the bad and the ugly. Estrogen; such a familiar hormone, and such a large influence on everyone’s health, female or male, young or old. With an abundance of estrogen during women’s reproductive [...]

MERIT Program Announced at CNPRC

Igniting Novel Research with Current and New Animal Models Drug discovery and innovative therapeutic approaches in the era of personalized medicine requires the use of animal models that closely recapitulate human disease. To address these challenges, the California National Primate Research Center (CNPRC) at UC Davis is initiating the MERIT [...]

Understanding Pre-term Labor for Diagnostics and Therapeutics

Research conducted at the CNPRC on chorioamnionitis-induced preterm labor in women has been recommended by Faculty of 1000, in recognition of the research’s high impact in its field. Faculty of 1000 is a collaboration of over 5,000 world-wide faculty experts who identify important articles in biology and medical research publications. [...]

Binge drinking: implications for human health

Think before you drink.
 "Dry January" can be a struggle for some after the holidays, but new research has revealed that you may be benefiting your own and future offspring’s health. A new study by CNPRC Core Scientist Catherine VandeVoort, PhD, (Fetility and Sterility) identified some of the potential effects of long-term [...]

2017-08-30T23:07:09+00:00 January 13th, 2015|Tags: , , , , |

Predicting embryo success with in vitro fertilization

According to the American Society for Reproductive Medicine, just 7.5 percent of all artificially fertilized embryos will go on to become live-born children. With such a low success rate, failed in vitro fertilization (IVF) is a frustrating situation for couples and their doctors. Stuart Meyers, D.V.M., Ph.D., CNPRC Affiliate Scientist [...]

Why Primate Models Matter

Scientists discuss the importance of primate models for advancing knowledge in biomedical and biological research. Presenting an honest, forthright discussion of the ethical considerations of using nonhuman primates (NHP) in research, and demonstrating the vital role NHP have played in many of the medical and scientific advances of the past [...]

2017-08-30T23:07:10+00:00 April 15th, 2014|Tags: , |

Dietary Sugar Affects Oocytes

Research links sugar consumption to disrupted ovarian function in healthy animals CNPRC housed rhesus monkeys fed relatively low doses of dietary sugar over 6 months showed significant impairments in oocyte maturation and major changes in early embryo gene expression, according to researchers Charles L. Chaffin, PhD (University of Maryland School [...]

2017-08-30T23:07:10+00:00 April 14th, 2014|Tags: , , , |

Tissue Engineering Research Funded by CIRM

A UC Davis team, co-led by Alice Tarantal, PhD, and Peter Belafsky, MD, MPH, PhD, has received a $4.4 million grant from the California Institute for Regenerative Medicine (CIRM) for their project entitled “Tissue Engineered Recellularized Laryngotracheal Implants”, which proposes to develop a stem cell-derived airway transplant to cure a difficult, life-threatening [...]

2017-08-30T23:07:10+00:00 December 12th, 2013|Tags: , , |

Formula-fed Babies May be More Susceptible to Chronic Disease

Formula-fed infants experience metabolic stress that could make them more susceptible than breast-fed infants to a wide range of health issues such as obesity, diabetes, liver problems and cardiovascular disease, according to new research conducted at the CNPRC by biochemists Carolyn Slupsky and Bo Lönnerdal, both of the UC Davis [...]

2017-08-30T23:07:10+00:00 August 8th, 2013|Tags: , , , |

BPA Affects Lung Development

Collaborative efforts add critical information to understanding effects of BPA BPA (bisphenol A), is used in the manufacturing of various plastics and food packaging, consumer products, some paper receipts, and medical devices. It is controversial because it exerts weak, but detectable, hormone-like properties which can mimic estrogen and may lead [...]

2017-08-30T23:07:10+00:00 August 1st, 2013|Tags: , , |

Maternal Antibodies Linked to Autism

In a major advance in understanding risk factors, and possible means of prevention of autism, Melissa Bauman, PhD, and David Amaral, PhD, performed studies at the CNPRC with rhesus monkeys to further define the role that maternal antibodies have to play in the risk of a child having autism. The research was [...]

2014-06-06T16:16:42+00:00 July 9th, 2013|Tags: , , |

BPA Shows Two-generation Effect

Exposure of pregnant monkeys to the widely-used chemical bisphenol A (BPA) disrupts development of fetal ovaries, potentially causing birth defects and reproductive problems that would not emerge for a generation, according to research by Dr. Patricia Hunt and colleagues at Washington State University and Dr. Catherine VandeVoort at the CNPRC. [...]

2017-08-30T23:07:10+00:00 September 24th, 2012|Tags: , , , |

BPA and Female Development

Adding important new findings to extensive scientific evidence that Bisphenol A (BPA) is a harmful substance, Dr. Catherine VandeVoort, staff scientist in Reproductive Sciences and Regenerative Medicine at the CNPRC, has been part of a team effort investigating the effects of BPA on the fetal development in nonhuman primates and [...]

2017-08-30T23:07:10+00:00 May 28th, 2012|Tags: , , |