The in vivo imaging program provides a unique depth and breadth of services offered for whole-animal imaging to meet a broad spectrum of investigator and colony needs. The Core functions within an organized structure with a high level of expertise for imaging and interpretation.
The Core develops innovative methods and techniques using state-of-the-art technologies. One of the Core objectives is to validate the rhesus monkey model for lifespan health research initiatives. New imaging paradigms under development focus on maternal/fetal imaging and the multimodal application of ultrasound imaging with bioluminescence imaging and PET/CT. The Core has also developed a complement of new techniques including those used to explore the pharmacokinetics of novelradiopharmaceuticals by high performance liquid chromatography (HPLC).
In Vivo Imaging Capabilities
This program has allowed investigators to incorporate non-invasive ultrasound-related techniques and procedures in their research programs, and to use non-surgical ultrasound-guided methods to develop new monkey models of human disease.
- Ultrasound imaging includes a spectrum of applications during pregnancy and an array of ultrasound-guided procedures that provide an efficient means for sample collection and delivery into a variety of anatomical locations in all age groups (fetal to aged).
- From a colony management perspective, established fetal growth charts are routinely used to confirm gestational age in time-mated animals, and to predict gestational age in outdoor-housed animals where the time of conception is not known. Time-mated animals are screened annually, and for assignment to research projects.
- GE Discovery® 610 PET/CT Imaging System provides a spectrum of new opportunities for research and expands existing capabilities in translational in vivo imaging for investigators. This system also provides important translational imaging opportunities to assess, for example, new radiopharmaceuticals for human imaging.
- Optical imaging
- Radiochemistry and Radiochemistry Research and Training Facility
- Pharmacokinetic analyses of new radiopharmaceuticals
- Histology: Routine and custom services
- Microscopy and Digital Imaging: Routine and custom services
- Whole slide scanning (The whole slide scanner is available as a service only.)
The University has established recharge rates. Costs will vary based on the services, equipment, and experimental protocol used.
For a cost estimate, to receive information on rates, and for other questions please contact:
Alice Tarantal, Ph.D.